Dr. William Panenka

View an extended list of peer-reviewed publications on PubMed

• Zhou LW, Panenka WJ, Jones AA, Gicas KM, Thornton AE, Heran MKS, Volders D, Lang DJ, Vertinsky AT, Rauscher A, Su W, Barr AM, MacEwan GW, Honer WG, Field TS. Prevalence and Risk Factors of Brain Infarcts and Associations With Cognitive Performance in Tenants of. Marginal Housing. J Am Heart Assoc. 2019 July 2. doi: 10.1161/JAHA.118.011412.
• Alexander PD, Gicas KM, Cheng A, Lang DJ, Procyshyn RM, Vertinsky AT, Panenka WJ, Thornton AE, Rauscher A, Wong JYX, Chan T, Jones AA, Vila-Rodriguez F, Honer WG, Barr AM. A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia. Psychopharmacology. 2019 June 22. doi: 10.1007/s00213-019-05298-w.
• Iverson GL, Cook NE, Howell DR, Collings LJ, Kusch C, Sun J, Virji-Babul N, Panenka WJ. Preseason Vestibular Ocular Motor Screening in Children and Adolescents. Clin J Sport Med. 2019 June 19. doi: 10.1097/JSM.0000000000000767
• Gicas KM, Jones AA, Panenka WJ, Giesbrecht C, Lang DJ, Vila-Rodriguez F, Leonova O, Barr AM, Procyshyn RM, Su W, Rauscher A, Vertinsky AT, Buchanan T, MacEwan GW, Thornton AE, Honer WG. Cognitive profiles and associated structural brain networks in a multmorbid sample of marginalized adults. PLoS One. 2019 June 13. doi: 10.1371/journal.pone.0218201
• Silverberg ND, & Panenka WJ. Antidepressants for depression after concussion and traumatic brain injury are still best practice. BMC Psychiatry. 2019 Mar 27. 19(1), 100. https://doi.org/10.1186/s12888-019-2076-6
• Gicas KM, Cheng A, Rawtaer I, Willi TS, Panenka WJ, Lang DJ, Smith GN, Vila-Rodriguez F, Leonova O, Giesbrecht CJ, Jones AA, Barr AM, Procyshyn RM, Buchanan T, MacEwan GW, Su W, Vertinsky AT, Rauscher A, O’Rourke N, Loken Thornton W, Thornton AE, Honer WG. Diffusion tensor imaging of neurocognitive profiles in a community cohort living in marginal housing. Brain Behav. 2019 Mar;9(3):e01233. doi: 10.1002/brb3.1233. Epub 2019 Feb 6
• Reed N, Silverberg ND, Iaccarino MA, McCrea M, McCulloch KL, Panenka WJ, Gregory E, Dams-O’Connor K, Iverson GL, Weyer Jamora C, Belanger H, McKinney G, Cogan AM, Provvidenza C. Returning to Activity After a Concussion. Arch Phys Med Rehabil. 2019 Jan 30. doi: 10.1016/j.apmr.2018.11.022
• Stubbs JL, Coorow SL, Kiang BR, Corrow JC, Pearce HL, Cheng AY, Barton JJS, Panenka WJ. Working memory load improves diagnostic performance of smooth pursuit eye movement in mild traumatic brain injury patients with protracted recovery. Sci Rep. 2019 Jan 22. doi: 10.1038/s41598-018-36286-3
• Silverberg ND, Martin P, Panenka WJ. Headache trigger sensitivity and avoidance after mild traumatic brain injury. J Neurotrauma. 2019 May 15;36(10):1544-1550. doi: 10.1089/neu.2018.6025. Epub 2019 Jan 11
• Terry DP, Brassil M, Iverson GL, Panenka WJ, Silverberg ND. Effect of depression on cognition after mild traumatic brain injury in adults. Clin Neuropsychol. 2019 Jan;33(1):124-136. doi: 10.1080/13854046.2018.1459853. Epub 2018 May 4
• Gicas KM, Thornton AE, Waclawik K, Wang N, Jones AA, Panenka WJ, Lang DJ, Smith GN, Vila-Rodriguez F, Leonova O, Barr AM, Procyshyn RM, Buchanan T, Su W, Vertinsky AT, Rauscher A, MacEwan GW, Honer WG. Volumes of the Hippocampal Formation Differentiate Component Processes of Memory in a Community Sample of Homeless and Marginally Housed Persons. Arch Clin Neuropsychol. 2018 Nov 8. doi: 10.1093/arclin/acy066. [Epub ahead of print]
• Silverberg ND, Panenka WJ, Iverson GL. Fear Avoidance and Clinical Outcomes from Mild Traumatic Brain Injury. J Neurotrauma. 2018 Aug 15;35(16):1864-1873. doi: 10.1089/neu.2018.5662
• Terry DP, Iverson GL, Panenka WJ, Colantonio A, Silverberg ND. Workplace and non-workplace mild traumatic brain injuries in an outpatient clinic sample: A case-control study. PLoS One. 2018 Jun 1;13(6):e0198128. doi: 10.1371/journal.pone.0198128. eCollection 2018
• Barbic SP, Jones AA, Woodward M, Piercy M, Mathias S, Vila-Rodriguez F, Leonova O, Smith GN, Buchanan T, Vertinsky AT, Gillingham S, Panenka WJ, Rauscher A, Barr AM, Procyshyn RM, MacEwan GW, Lang DJ, Thornton AE, Heran MK, Leon AM, Krausz M, Honer WG. Clinical and functional characteristics of young adults living in single room occupancy housing: preliminary findings from a 10-year longitudinal study. Can J Public Health. 2018 Apr;109(2):204-214. doi: 10.17269/s41997-018-0087-9. Epub 2018 May 31
• Iverson GL, Terry DP, Karr JE, Panenka WJ, Silverberg ND. Perceived Injustice and Its Correlates after Mild Traumatic Brain Injury. J Neurotrauma. 2018 May 15;35(10):1156-1166. doi: 10.1089/neu.2017.5402. Epub 2018 Mar 1
• Jones AA, Jang K, Panenka WJ, Barr AM, MacEwan GW, Thornton AE, Honer WG. Rapid Change in Fentanyl Prevalence in a Community-Based, High-Risk Sample. JAMA Psychiatry. 2018 Mar 1;75(3):298-300. doi: 10.1001/jamapsychiatry.2017.4432.
• Silverberg ND, Panenka WJ, Iverson GL. Work Productivity Loss After Mild Traumatic Brain Injury. Arch Phys Med Rehabil. 2018 Feb;99(2):250-256. doi: 10.1016/j.apmr.2017.07.006. Epub 2017 Jul 29.
• Stubbs JL, Corrow SL, Kiang B, Panenka WJ, Barton JJS. The effects of enhanced attention and working memory on smooth pursuit eye movement. Exp Brain Res. 2018 Feb;236(2):485-495. doi: 10.1007/s00221-017-5146-6. Epub 2017 Dec 8.
• Luoto TM, Raj R, Posti JP, Gardner AJ, Panenka WJ, Iverson GL. A Systematic Review of the Usefulness of Glial Fibrillary Acidic Protein for Predicting Acute Intracranial Lesions following Head Trauma. Front Neurol. 2017 Dec 4;8:652. doi: 10.3389/fneur.2017.00652
• Collings LJ, Cook NE, Porter S, Kusch C, Sun J, Virji-Babul N, Iverson GL, Panenka WJ. Attention-deficit/hyperactivity disorder is associated with baseline child sport concussion assessment tool third edition scores in child hockey players. Brain Inj. 2017;31(11):1479-1485. doi: 10.1080/02699052.2017.1377351. Epub 2017 Oct 5.
• Snell D, Iverson GL, Panenka WJ, Silverberg ND. Preliminary validation of the World Health Organization Disability Assessment Schedule 2.0 for Mild Traumatic Brain Injury. J Neurotrauma. 2017 Dec 1;34(23):3256-3261. doi: 10.1089/neu.2017.5234. Epub 2017 Oct 16.
• Porter S, Torres IJ, Panenka WJ, Rajwani Z, Fawcett D, Hyder A, Virji-Babul N. Changes in brain-behavior relationships following a 3-month pilot cognitive intervention program for adults with traumatic brain injury. Heliyon. 2017 Aug 4. 3(8): e00373. doi: 10.1016/j.heliyon.2017
• Schmitt T, Thornton A, Rawtaer I, Barr A, Gicas K, Lang D, Vertinsky T, Rauscher A, Procyshyn R, Buchanan T, Cheng A, Mackay S, Leonova O, Langheimer V, Field T, Heran MKS, Vila-Rodriguez F, O’Connor TA, MacEwan W, Honer W, Panenka WJ. Traumatic Brain Injury in a Community-Based Cohort of Homeless and Vulnerably Housed Individuals. Neurotrauma. 2017 Jul 25. doi: 10.1089/neu.2017.5076.
• Stax AM, Tuengel J, Girardi E, Kitano N, Allan LL, Li V, Zheng D, Panenka WJ, Guillaume J, Wong CH, Calenbergh S, Zajonc DM, Elzen P. Autoreactivity to Sulfatide by Human Invariant NKT Cells. J Immunology. 2017 Jul 1;199(1):97-106. doi: 10.4049/jimmunol.1601976. Epub 2017 May 19.
• Panenka WJ, Gardner AJ, Dretsch MN, Crynen GC, Crawford FC, Iverson GL. Systematic Review of Genetic Risk Factors for Sustaining a Mild Traumatic Brain Injury. J Neurotrauma. 2017 Jul 1;34(13):2093-2099. doi: 10.1089/neu.2016.4833. Epub 2017 Feb 27.
• Silverberg ND, Iverson GL, Panenka WJ. Cogniphobia in Mild Traumatic Brain Injury. J Neurotrauma. 2017 Jul 1;34(13):2141-2146. doi: 10.1089/neu.2016.4719. Epub 2017 Feb 27.
• Dretsch MN, Silverberg N, Gardner AJ, Panenka WJ, Emmerich T, Crynen G, Ait-Ghezala G, Chaytow H, Mathura V, Crawford FC, Iverson GL. Genetics and Other Risk Factors for Past Concussions in Active-Duty Soldiers. J Neurotrauma. 2017 Feb 15;34(4):869-875. doi: 10.1089/neu.2016.4480.
• Alexander PD, Gicas KM, Willi TS, Kim CN, Boyeva V, Procyshyn RM, Smith GN, Thornton AE, Panenka WJ, Jones AA, Vila-Rodriguez F, Lang DJ, MacEwan GW, Honer WG, Barr AM. A comparison of psychotic symptoms in subjects with methamphetamine versus cocaine dependence. Psychopharmacology (Berl). 2017 May;234(9-10):1535-1547. doi: 10.1007/s00213-017-4551-7. Epub 2017 Feb 11.
• Gicas KM, Giesbrecht CJ, Panenka WJ, Lang DJ, Smith GN, Vila-Rodriguez F, Leonova O, Jones AA, Barr AM, Procyshyn RM, Buchanan T, MacEwan GW, Su W, Vertinsky AT, Rauscher A, Honer WG, Thornton AE. Structural brain markers are differentially associated with neurocognitive profiles in socially marginalized people with multimorbid illness. Neuropsychology. 2017 Jan;31(1):28-43. doi: 10.1037/neu0000304.
• Honer WG, Cervantes-Larios A, Jones AA, Vila-Rodriguez F, Montaner JS, Tran H, Nham J, Panenka WJ, Lang DJ, Thornton AE, Vertinsky T, Barr AM, Procyshyn RM, Smith GN, Buchanan T, Krajden M, Krausz M, MacEwan GW, Gicas KM, Leonova O, Langheimer V, Rauscher A, Schultz K. The Hotel Study-Clinical and Health Service Effectiveness in a Cohort of Homeless or Marginally Housed Persons. Can J Psychiatry. 2017 Jul;62(7):482-492. doi: 10.1177/0706743717693781. Epub 2017 Feb 15.
• Willi TS, Barr AM, Gicas K, Lang DJ, Vila-Rodriguez F, Su W, Thornton AE, Leonova O, Giesbrecht CJ, Procyshyn RM, Rauscher A, MacEwan WG, Honer WG, Panenka WJ. Characterization of white matter integrity deficits in cocaine-dependent individuals with substance-induced psychosis compared with non-psychotic cocaine users. Addict Biol. 2017 May;22(3):873-881. doi: 10.1111/adb.12363. Epub 2016 Feb 1.
• Willi TS, Lang DJ, Honer WG, Smith GN, Thornton AE, Panenka WJ, Procyshyn RM, Vila-Rodriguez F, Su W, Vertinsky AT, Leonova O, Rauscher A, MacEwan GW, Barr AM. Subcortical grey matter alterations in cocaine dependent individuals with substance-induced psychosis compared to non-psychotic cocaine users. Schizophr Res. 2016 Oct;176(2-3):158-63. doi: 10.1016/j.schres.2016.08.001.
• Silverberg ND, Panenka WJ, Iverson GL, Brubacher JR, Shewchuk JR, Heran MK, Oh GC, Honer WG, Lange RT. Alcohol Consumption Does not Impede Recovery from Mild to Moderate Traumatic Brain Injury. J Int Neuropsychol Soc. 2016 Sep;22(8):816-27. doi: 10.1017/S1355617716000692.
• Willi TS, Honer WG, Thornton AE, Gicas K, Procyshyn RM, Vila-Rodriguez F, Panenka WJ, Aleksic A, Leonova O, Jones AA, MacEwan GW, Barr AM. Factors affecting severity of positive and negative symptoms of psychosis in a polysubstance using population with psychostimulant dependence. Psychiatry Res. 2016 Jun 30;240:336-42. doi: 10.1016/j.psychres.2016.04.059.
• Giesbrecht CJ, O’Rourke N, Leonova O, Strehlau V, Paquet K, Vila-Rodriguez F, Panenka WJ, MacEwan GW, Smith GN, Thornton AE, Honer WG. The Positive and Negative Syndrome Scale (PANSS): A Three-Factor Model of Psychopathology in Marginally Housed Persons with Substance Dependence and Psychiatric Illness. PLoS One. 2016 Mar 21;11(3):e0151648. doi: 10.1371/journal.pone.0151648.
• Tang VM, Lang DJ, Giesbrecht CJ, Panenka WJ, Willi T, Procyshyn RM, Vila-Rodriguez F, Jenkins W, Lecomte T, Boyda HN, Aleksic A, MacEwan GW, Honer WG, Barr AM. White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection. BMC Res Notes. 2015 Sep 30;8:515. doi: 10.1186/s13104-015-1501-5.
• Porter S, Smith-Forrester J, Alhajri N, Kusch C, Sun J, Barrable B, Panenka WJ, Virji-Babul N. The Child Sport Concussion Assessment Tool (Child SCAT3): normative values and correspondence between child and parent symptom scores in male child athletes. BMJ Open Sport Exerc Med. 2015 Aug 21;1(1):e000029.
• Jones AA, Vila-Rodriguez F, Leonova O, Langheimer V, Lang DJ, Barr AM, Procyshyn RM, Smith GN, Schultz K, Buchanan T, Krausz M, Montaner JS, MacEwan GW, Rauscher A, Panenka WJ, Thornton AE, Honer WG. Mortality from treatable illnesses in marginally housed adults: a prospective cohort study. BMJ Open. 2015 Aug 21;5(8):e008876. doi: 10.1136/bmjopen-2015-008876.
• Panenka WJ, Lange RT, Bouix S, Shewchuk JR, Heran MK, Brubacher JR, Eckbo R, Shenton ME, Iverson GL. Neuropsychological outcome and diffusion tensor imaging in complicated versus uncomplicated mild traumatic brain injury. PLoS One. 2015 Apr 27;10(4):e0122746. doi: 10.1371/journal.pone.0122746.
• Silverberg ND, Gardner AJ, Brubacher JR, Panenka WJ, Li JJ, Iverson GL. Systematic review of multivariable prognostic models for mild traumatic brain injury. J Neurotrauma. 2015 Apr 15;32(8):517-26. doi: 10.1089/neu.2014.3600. Review.
• Lange RT, Panenka WJ, Shewchuk JR, Heran MK, Brubacher JR, Bioux S, Eckbo R, Shenton ME, Iverson GL. Diffusion tensor imaging findings and postconcussion symptom reporting six weeks following mild traumatic brain injury. Arch Clin Neuropsychol. 2015 Feb;30(1):7-25. doi: 10.1093/arclin/acu060.
• Procyshyn RM, Su J, Elbe D, Liu AY, Panenka WJ, Davidson J, Honer WG, Barr AM. Prevalence and patterns of antipsychotic use in youth at the time of admission and discharge from an inpatient psychiatric facility. J Clin Psychopharmacol. 2014 Feb;34(1):17-22. doi: 10.1097/JCP.0b013e3182a607dd.
• Gicas KM, Vila-Rodriguez F, Paquet K, Barr AM, Procyshyn RM, Lang DJ, Smith GN, Baitz HA, Giesbrecht CJ, Montaner JS, Krajden M, Krausz M, MacEwan GW, Panenka WJ, Honer WG, Thornton AE. Neurocognitive profiles of marginally housed persons with comorbid substance dependence, viral infection, and psychiatric illness. J Clin Exp Neuropsychol. 2014;36(10):1009-22. doi: 10.1080/13803395.2014.963519.
• Vila-Rodriguez F, Panenka WJ, Lang DJ, Thornton AE, Vertinsky T, Wong H, Barr AM, Procyshyn RM, Sidhu JJ, Smith GN, Buchanan T, Krajden M, Krausz M, Montaner JS, MacEwan GW, Honer WG. The hotel study: multimorbidity in a community sample living in marginal housing. Am J Psychiatry. 2013 Dec;170(12):1413-22. doi: 10.1176/appi.ajp.2013.12111439.
• Jones AA, Vila-Rodriguez F, Panenka WJ, Leonova O, Strehlau V, Lang DJ, Thornton AE, Wong H, Barr AM, Procyshyn RM, Smith GN, Buchanan T, Krajden M, Krausz M, Montaner JS, Macewan GW, Nutt DJ, Honer WG. Personalized risk assessment of drug-related harm is associated with health outcomes. PLoS One. 2013 Nov 6;8(11):e79754. doi: 10.1371/journal.pone.0079754.
• Namjoshi DR, Good C, Cheng WH, Panenka WJ, Richards D, Cripton PA, Wellington CL. Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective. Dis Model Mech. 2013 Nov;6(6):1325-38. doi: 10.1242/dmm.011320. Review.
• Panenka WJ, Procyshyn RM, Lecomte T, MacEwan GW, Flynn SW, Honer WG, Barr AM. Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings. Drug Alcohol Depend. 2013 May 1;129(3):167-79. doi: 10.1016/j.drugalcdep.2012.11.016. Review.
• Barr AM, Panenka WJ, Honer WG, Khara S, Procyshyn RM. Excessive antipsychotic dosing in a Canadian outpatient population. Psychiatry Serv. 2011 Jun;62(6):682-3. doi: 10.1176/ps.62.6.pss6206_0682a.
• Panenka WJ, Khorram B, Barr AM, Smith GN, Lang DJ, Kopala LC, Vandorpe RA, Honer WG. A longitudinal study on the effects of typical versus atypical antipsychotic drugs on hippocampal volume in schizophrenia. Schizophr Res. 2007 Aug;94(1-3):288-92.
• Barr AM, Panenka WJ, MacEwan GW, Thornton AE, Lang DJ, Honer WG, Lecomte T. The need for speed: an update on methamphetamine addiction. J Psychiatry Neurosci. 2006 Sep;31(5):301-13. Review.
• Darby M, Kuzmiski JB, Panenka WJ, Feighan D, MacVicar BA. ATP released from astrocytes during swelling activates chloride channels. J Neurophysiol. 2003 Apr;89(4):1870-7.
• Jijon HB, Panenka WJ, Madsen KL, Parsons HG. MAP kinases contribute to IL-8 secretion by intestinal epithelial cells via a posttranscriptional mechanism. Am J Physiol Cell Physiol. 2002 Jul;283(1):C31-41.
• Panenka WJ, Jijon H, Herx LM, Armstrong JN, Feighan D, Wei T, Yong VW, Ransohoff RM, MacVicar BA. P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. J Neurosci. 2001 Sep 15;21(18):7135-42.
• Crépel V, Panenka WJ, Kelly ME, MacVicar BA. Mitogen-activated protein and tyrosine kinases in the activation of astrocyte volume-activated chloride current. J Neurosci. 1998 Feb 15;18(4):1196-206.